Cnga1 - cyclic nucleotide gated channel alpha 1

Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in membrane depolarization and regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within ion transport and visual perception. Located in photoreceptor outer segment membrane. Is expressed in photoreceptor layer outer segment; retina; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 49. Orthologous to human CNGA1 (cyclic nucleotide gated channel subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]