Ackr3 - atypical chemokine receptor 3

Predicted to enable chemokine binding activity; chemokine receptor activity; and scavenger receptor activity. Acts upstream of or within negative regulation of cell population proliferation and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in several cellular components, including cell surface; clathrin-coated pit; and endosome. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including adrenal gland; central nervous system; genitourinary system; heart; and hemolymphoid system. Orthologous to human ACKR3 (atypical chemokine receptor 3). [provided by Alliance of Genome Resources, Apr 2022]