Clcn1 - chloride channel, voltage-sensitive 1

Predicted to enable protein homodimerization activity and voltage-gated chloride channel activity. Acts upstream of or within chloride transport and neuronal action potential propagation. Located in sarcolemma. Is expressed in central nervous system; early conceptus; heart; oocyte; and retina. Used to study myotonia congenita. Human ortholog(s) of this gene implicated in myotonia congenita. Orthologous to human CLCN1 (chloride voltage-gated channel 1). [provided by Alliance of Genome Resources, Apr 2022]