Cidea - cell death-inducing DNA fragmentation factor, alpha subunit-like effector A

Enables protein homodimerization activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of sequestering of triglyceride. Acts upstream of or within lipid metabolic process and response to stilbenoid. Located in mitochondrial envelope and nucleus. Colocalizes with lipid droplet. Is expressed in brown fat. Human ortholog(s) of this gene implicated in obesity. Orthologous to human CIDEA (cell death inducing DFFA like effector a). [provided by Alliance of Genome Resources, Apr 2022]