Cel - carboxyl ester lipase

Predicted to enable several functions, including carboxylic ester hydrolase activity; glycosphingolipid binding activity; and neurexin family protein binding activity. Acts upstream of or within ceramide catabolic process. Predicted to be located in several cellular components, including membrane raft; rough endoplasmic reticulum; and zymogen granule. Predicted to be part of protein-containing complex. Predicted to be active in cell surface and synapse. Predicted to be integral component of postsynaptic specialization membrane. Is expressed in several structures, including gut and mammary gland. Human ortholog(s) of this gene implicated in lipomatosis; maturity-onset diabetes of the young type 8; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human CEL (carboxyl ester lipase). [provided by Alliance of Genome Resources, Apr 2022]