Cebpb - CCAAT/enhancer binding protein (C/EBP), beta
Alias:
LAP
LIP
CRP2
NF-M
Nfil6
NF-IL6
IL-6DBP
C/EBPbeta
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II core promoter sequence-specific DNA binding activity; and enzyme binding activity. Contributes to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including liver development; regulation of leukocyte differentiation; and response to bacterium. Acts upstream of or within several processes, including mammary gland epithelium development; positive regulation of osteoblast differentiation; and regulation of gene expression. Located in chromosome; cytoplasm; and nuclear matrix. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including adrenal gland; alimentary system; extraembryonic component; genitourinary system; and integumental system. Used to study cleidocranial dysplasia and viral infectious disease. Orthologous to human CEBPB (CCAAT enhancer binding protein beta). [provided by Alliance of Genome Resources, Apr 2022]