Cbs - cystathionine beta-synthase

Enables cystathionine beta-synthase activity. Acts upstream of or within several processes, including alpha-amino acid metabolic process; endochondral bone morphogenesis; and regulation of JUN kinase activity. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; connective tissue; nervous system; sensory organ; and skeleton. Used to study homocystinuria. Human ortholog(s) of this gene implicated in coronary artery disease; homocystinuria; hyperhomocysteinemia; malaria; and neural tube defect. Orthologous to human CBS (cystathionine beta-synthase). [provided by Alliance of Genome Resources, Apr 2022]