Enables calcium-dependent cysteine-type endopeptidase activity. Involved in cellular response to amino acid stimulus and proteolysis. Acts upstream of or within blastocyst development and myoblast fusion. Located in several cellular components, including chromatin; cytosol; and lysosome. Is expressed in several structures, including hindbrain; lens epithelium; oral region epithelium; skin; and spinal cord floor plate. Orthologous to human CAPN2 (calpain 2). [provided by Alliance of Genome Resources, Apr 2022]