Enables calcium ion binding activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium ion binding activity involved in regulation of presynaptic cytosolic calcium ion concentration. Involved in regulation of long-term synaptic potentiation. Acts upstream of or within several processes, including locomotory behavior; metanephros development; and retina layer formation. Located in several cellular components, including GABA-ergic synapse; hippocampal mossy fiber to CA3 synapse; and neuronal cell body. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; lung; nervous system; and sensory organ. Orthologous to human CALB1 (calbindin 1). [provided by Alliance of Genome Resources, Apr 2022]