Cacna1g - calcium channel, voltage-dependent, T type, alpha 1G subunit
Alias:
a1G
[a]1G
Cav3.1d
alpha-1G
mKIAA1123
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables low voltage-gated calcium channel activity; voltage-gated calcium channel activity involved SA node cell action potential; and voltage-gated calcium channel activity involved in AV node cell action potential. Involved in calcium ion transmembrane transport; cardiac conduction; and cardiac muscle cell action potential involved in contraction. Acts upstream of or within several processes, including regulation of atrial cardiac muscle cell membrane depolarization; regulation of heart rate; and response to nickel cation. Located in plasma membrane. Part of voltage-gated calcium channel complex. Is expressed in central nervous system; heart; hindlimb musculature; lower jaw molar; and retina. Used to study cerebellar ataxia type 42. Human ortholog(s) of this gene implicated in cerebellar ataxia type 42. Orthologous to human CACNA1G (calcium voltage-gated channel subunit alpha1 G). [provided by Alliance of Genome Resources, Apr 2022]