Enables high voltage-gated calcium channel activity. Acts upstream of or within several processes, including calcium ion transmembrane transport; neurotransmitter secretion; and response to pain. Located in dendrite; membrane; and neuronal cell body. Part of voltage-gated calcium channel complex. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and retina. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome and dystonia 23. Orthologous to human CACNA1B (calcium voltage-gated channel subunit alpha1 B). [provided by Alliance of Genome Resources, Apr 2022]