Btrc - beta-transducin repeat containing protein

Enables beta-catenin binding activity; protein phosphorylated amino acid binding activity; and ubiquitin protein ligase activity. Involved in several processes, including cellular protein metabolic process; positive regulation of circadian rhythm; and regulation of canonical Wnt signaling pathway. Acts upstream of or within several processes, including mammary gland epithelium development; protein K48-linked ubiquitination; and regulation of I-kappaB kinase/NF-kappaB signaling. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; peripheral nervous system; and respiratory system. Orthologous to human BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Apr 2022]