Bglap3 - bone gamma-carboxyglutamate protein 3

Predicted to enable calcium ion binding activity and hydroxyapatite binding activity. Predicted to be a structural constituent of bone. Predicted to be involved in bone development and osteoblast differentiation. Predicted to act upstream of or within biomineral tissue development. Predicted to be located in several cellular components, including Golgi apparatus; perikaryon; and rough endoplasmic reticulum. Predicted to be active in extracellular region. Is expressed in several structures, including cranial ganglion; endocrine gland; nasal cavity epithelium; respiratory system; and thymus primordium. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein). [provided by Alliance of Genome Resources, Apr 2022]