Atp4b - ATPase, H+/K+ exchanging, beta polypeptide

Predicted to enable ATPase activator activity and P-type potassium:proton transporter activity. Predicted to contribute to heterocyclic compound binding activity. Predicted to be involved in cellular monovalent inorganic cation homeostasis and inorganic cation transmembrane transport. Predicted to act upstream of or within pH reduction; protein glycosylation in endoplasmic reticulum; and regulation of proton transport. Predicted to be located in endoplasmic reticulum and plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Is expressed in alimentary system; stomach; stomach epithelium; stomach fundus; and stomach mucosa. Human ortholog(s) of this gene implicated in atrophic gastritis; autoimmune gastritis; and stomach cancer. Orthologous to human ATP4B (ATPase H+/K+ transporting subunit beta). [provided by Alliance of Genome Resources, Apr 2022]