Arg2 - arginase type II

Predicted to enable arginase activity; manganese ion binding activity; and nitric-oxide synthase binding activity. Involved in several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process; and negative regulation of cytokine production. Acts upstream of or within striated muscle contraction and ureteric bud development. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ARG2 (arginase 2). [provided by Alliance of Genome Resources, Apr 2022]