Arf1 - ADP-ribosylation factor 1

Enables GTP binding activity and magnesium ion binding activity. Involved in mitotic cleavage furrow ingression. Acts upstream of or within vesicle-mediated transport. Located in Golgi apparatus; cytosol; and sarcomere. Part of protein-containing complex. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; integumental system; and nervous system. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ADP ribosylation factor 1). [provided by Alliance of Genome Resources, Apr 2022]