Srgap1 - SLIT-ROBO Rho GTPase activating protein 1

Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within Rho protein signal transduction and cell migration. Predicted to be active in cytoplasm. Is expressed in nervous system and s-shaped body. Human ortholog(s) of this gene implicated in thyroid gland papillary carcinoma. Orthologous to human SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1). [provided by Alliance of Genome Resources, Apr 2022]