Predicted to enable ATP binding activity and hydrolase activity. Predicted to be involved in vacuolar acidification. Is integral component of membrane. Part of vacuolar proton-transporting V-type ATPase, V1 domain. Human ortholog(s) of this gene implicated in autosomal dominant congenital deafness with onychodystrophy. Orthologous to human ATP6V1B2 (ATPase H+ transporting V1 subunit B2). [provided by Alliance of Genome Resources, Apr 2022]