Baiap2 - BAR/IMD domain containing adaptor protein 2
Alias:
Irsp53
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables PDZ domain binding activity; scaffold protein binding activity; and transcription coregulator binding activity. Involved in several processes, including cellular response to L-glutamate; nervous system development; and regulation of synapse organization. Located in several cellular components, including dendrite; lamellipodium; and neuron projection branch point. Is active in several cellular components, including postsynaptic cytosol; postsynaptic density, intracellular component; and presynaptic cytosol. Colocalizes with postsynaptic density. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2). [provided by Alliance of Genome Resources, Apr 2022]