Aoc3 - amine oxidase, copper containing 3

Predicted to enable several functions, including metal ion binding activity; primary amine oxidase activity; and protein heterodimerization activity. Predicted to be involved in several processes, including leukocyte migration involved in inflammatory response; negative regulation of primary amine oxidase activity; and positive regulation of glucose transmembrane transport. Predicted to be located in several cellular components, including cell surface; extracellular space; and microvillus. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including Golgi apparatus; early endosome; and endoplasmic reticulum. Is expressed in several structures, including alimentary system; axial skeleton; cardiovascular system; sensory organ; and skin. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human AOC3 (amine oxidase copper containing 3). [provided by Alliance of Genome Resources, Apr 2022]