Anxa5 - annexin A5

Predicted to enable several functions, including P-type calcium transporter activity; calcium-dependent phospholipid binding activity; and receptor tyrosine kinase binding activity. Acts upstream of or within response to organic substance. Located in endothelial microparticle and external side of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; myocardial infarction; and systemic scleroderma. Orthologous to human ANXA5 (annexin A5). [provided by Alliance of Genome Resources, Apr 2022]