Ang2 - angiogenin, ribonuclease A family, member 2

Enables ribonuclease activity. Acts upstream of or within cell growth involved in cardiac muscle cell development; cellular response to glucose stimulus; and positive regulation of protein phosphorylation. Predicted to be located in several cellular components, including actin cytoskeleton; basement membrane; and nucleolus. Predicted to be active in extracellular space. Is expressed in cerebral cortex; cerebral cortex subventricular zone; and cerebral cortex ventricular layer. Human ortholog(s) of this gene implicated in diabetic retinopathy; myocardial infarction; neurodegenerative disease (multiple); and prostate cancer. Orthologous to human ANG (angiogenin). [provided by Alliance of Genome Resources, Apr 2022]