Park7 - Parkinsonism associated deglycase

Predicted to enable several functions, including enzyme activator activity; enzyme binding activity; and transition metal ion binding activity. Involved in several processes, including cellular response to lipopolysaccharide; negative regulation of NMDA glutamate receptor activity; and positive regulation of fertilization. Located in several cellular components, including membrane raft; mitochondrion; and sperm head. Used to study Parkinson's disease and Parkinsonism. Biomarker of Parkinsonism. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinson's disease 7; Parkinsonism; cerebral infarction; and middle cerebral artery infarction. Orthologous to human PARK7 (Parkinsonism associated deglycase). [provided by Alliance of Genome Resources, Apr 2022]