Ppp2r1a - protein phosphatase 2 scaffold subunit A alpha

Predicted to enable several functions, including protein antigen binding activity; protein heterodimerization activity; and protein serine/threonine phosphatase activity. Predicted to be involved in chromosome segregation and protein dephosphorylation. Predicted to act upstream of or within several processes, including nuclear division; peptidyl-serine dephosphorylation; and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in several cellular components, including chromosome, centromeric region; cytosol; and glutamatergic synapse. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytoplasm and synapse. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 36. Orthologous to human PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha). [provided by Alliance of Genome Resources, Apr 2022]