Nr0b2 - nuclear receptor subfamily 0, group B, member 2

Enables peroxisome proliferator activated receptor binding activity; retinoid X receptor binding activity; and thyroid hormone receptor binding activity. Involved in several processes, including animal organ regeneration; bile acid and bile salt transport; and positive regulation of insulin secretion. Part of protein-containing complex. Biomarker of alcoholic hepatitis; diabetes mellitus; and intrahepatic cholestasis. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR0B2 (nuclear receptor subfamily 0 group B member 2). [provided by Alliance of Genome Resources, Apr 2022]