Mt3 - metallothionein 3

Enables copper ion binding activity and zinc ion binding activity. Involved in brain development; negative regulation of hydrogen peroxide catabolic process; and negative regulation of neuron death. Located in several cellular components, including astrocyte end-foot; mitochondrial outer membrane; and synaptic vesicle. Used to study motor neuron disease. Biomarker of borna disease; cerebrovascular disease (multiple); hypothyroidism; median neuropathy; and visual epilepsy. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human MT3 (metallothionein 3). [provided by Alliance of Genome Resources, Apr 2022]