Ccr5 - C-C motif chemokine receptor 5

Enables protein kinase binding activity. Involved in several processes, including nervous system development; positive regulation of cytokine production; and response to bacterium. Located in cell surface and endosome. Used to study Alzheimer's disease; plague; and visual epilepsy. Biomarker of several diseases, including artery disease (multiple); diabetes mellitus (multiple); end stage renal disease; orchitis; and uveitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; West Nile fever; autoimmune disease (multiple); berylliosis; and sarcoidosis (multiple). Orthologous to human CCR5 (C-C motif chemokine receptor 5). [provided by Alliance of Genome Resources, Apr 2022]