Baz2a - bromodomain adjacent to zinc finger domain, 2A

Enables DNA binding activity; RNA binding activity; and lysine-acetylated histone binding activity. Involved in DNA methylation; histone deacetylation; and negative regulation of macromolecule metabolic process. Acts upstream of or within chromatin organization and histone modification. Located in nucleolus and rDNA heterochromatin. Part of chromatin silencing complex. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourinary system; and paraxial mesenchyme. Orthologous to human BAZ2A (bromodomain adjacent to zinc finger domain 2A). [provided by Alliance of Genome Resources, Apr 2022]