Lpar1 - lysophosphatidic acid receptor 1

Enables G-protein alpha-subunit binding activity and phospholipid binding activity. Involved in several processes, including cellular response to 1-oleoyl-sn-glycerol 3-phosphate; negative regulation of cAMP-mediated signaling; and nervous system development. Located in several cellular components, including dendrite; neuronal cell body; and plasma membrane. Used to study hepatocellular carcinoma and transient cerebral ischemia. Orthologous to human LPAR1 (lysophosphatidic acid receptor 1). [provided by Alliance of Genome Resources, Apr 2022]