Sh3gl2 - SH3 domain containing GRB2 like 2, endophilin A1
Alias:
Sh3p4
Sh3d2a
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables several functions, including identical protein binding activity; protein C-terminus binding activity; and protein kinase binding activity. Involved in several processes, including lipid tube assembly; positive regulation of membrane tubulation; and vesicle scission. Located in several cellular components, including basal dendrite; neuronal cell body; and perinuclear region of cytoplasm. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and synaptic vesicle membrane. Biomarker of visual epilepsy. Orthologous to human SH3GL2 (SH3 domain containing GRB2 like 2, endophilin A1). [provided by Alliance of Genome Resources, Apr 2022]