Enables ubiquitin-protein transferase activity. Predicted to be involved in several processes, including DNA repair; protein ubiquitination; and regulation of protein modification process. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm; fibrillar center; and nucleoplasm. Predicted to be part of UBC13-MMS2 complex; UBC13-UEV1A complex; and ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to several human genes including UBE2N (ubiquitin conjugating enzyme E2 N). [provided by Alliance of Genome Resources, Apr 2022]