Trim28 - tripartite motif-containing 28

Predicted to enable several functions, including promoter-specific chromatin binding activity; protein domain specific binding activity; and ubiquitin-like protein transferase activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of DNA methylation-dependent heterochromatin assembly; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within several processes, including DNA methylation involved in embryo development; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in euchromatin; heterochromatin; and nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in chromatin and nucleoplasm. Orthologous to human TRIM28 (tripartite motif containing 28). [provided by Alliance of Genome Resources, Apr 2022]