Lmnb1 - lamin B1

Predicted to enable phospholipase binding activity and sequence-specific double-stranded DNA binding activity. Involved in several processes, including cellular response to corticosterone stimulus; cellular response to monosodium L-glutamate; and response to antibiotic. Located in cytoplasm; nuclear membrane; and nuclear periphery. Human ortholog(s) of this gene implicated in adult-onset autosomal dominant demyelinating leukodystrophy and primary autosomal recessive microcephaly. Orthologous to human LMNB1 (lamin B1). [provided by Alliance of Genome Resources, Apr 2022]