Dusp6 - dual specificity phosphatase 6

Enables protein tyrosine/serine/threonine phosphatase activity. Involved in several processes, including negative regulation of ERK1 and ERK2 cascade; positive regulation of cell death; and response to growth factor. Located in cytosol. Biomarker of brain ischemia; pancreatitis; and visual epilepsy. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 19 with or without anosmia. Orthologous to human DUSP6 (dual specificity phosphatase 6). [provided by Alliance of Genome Resources, Apr 2022]