Tnc - tenascin C

Predicted to enable syndecan binding activity. Involved in several processes, including animal organ morphogenesis; cellular response to lipid; and cellular response to prostaglandin D stimulus. Located in extracellular matrix. Used to study pulmonary hypertension. Biomarker of cholangiocarcinoma; high grade glioma; myocardial infarction; polycystic kidney disease; and pulmonary hypertension. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; and autosomal dominant nonsyndromic deafness 56. Orthologous to human TNC (tenascin C). [provided by Alliance of Genome Resources, Apr 2022]