Wnk1 - WNK lysine deficient protein kinase 1

Enables several functions, including ATP binding activity; magnesium ion binding activity; and potassium channel inhibitor activity. Involved in several processes, including cellular response to calcium ion; negative regulation of sodium ion transport; and protein autophosphorylation. Located in cytosol and membrane. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 2A; hereditary sensory neuropathy; hypertension; and pseudohypoaldosteronism. Orthologous to human WNK1 (WNK lysine deficient protein kinase 1). [provided by Alliance of Genome Resources, Apr 2022]