Mapk8ip1 - mitogen-activated protein kinase 8 interacting protein 1
Alias:
JIP1
Jip-1
Mapk8ip
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables MAP-kinase scaffold activity; identical protein binding activity; and protein kinase binding activity. Involved in negative regulation of JUN kinase activity; negative regulation of apoptotic process; and signal transduction. Located in cytosol; growth cone; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]