Agtr1b - angiotensin II receptor, type 1b

Predicted to enable angiotensin receptor activity; bradykinin receptor binding activity; and protein heterodimerization activity. Involved in multicellular organism aging and regulation of blood pressure. Acts upstream of or within several processes, including blood vessel development; drinking behavior; and regulation of systemic arterial blood pressure by circulatory renin-angiotensin. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; genitourinary system; heart; liver; and lung. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; COVID-19; artery disease (multiple); chronic kidney disease; and sarcoidosis. Orthologous to human AGTR1 (angiotensin II receptor type 1). [provided by Alliance of Genome Resources, Apr 2022]