Enables G protein-coupled receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in axon terminus; cytoplasm; and neuronal cell body. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adrenal gland; central nervous system; early embryo; oocyte; and sensory organ. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human ADRA2C (adrenoceptor alpha 2C). [provided by Alliance of Genome Resources, Apr 2022]