Adra2a - adrenergic receptor, alpha 2a

Enables adrenergic receptor activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within G protein-coupled receptor signaling pathway and fear response. Is active in dopaminergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb segment; and sensory organ. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and type 2 diabetes mellitus. Orthologous to human ADRA2A (adrenoceptor alpha 2A). [provided by Alliance of Genome Resources, Apr 2022]