Adam9 - a disintegrin and metallopeptidase domain 9 (meltrin gamma)

Enables SH3 domain binding activity; metalloendopeptidase activity; and protein kinase C binding activity. Involved in several processes, including cell adhesion mediated by integrin; membrane protein ectodomain proteolysis; and positive regulation of membrane protein ectodomain proteolysis. Located in several cellular components, including cell surface; extracellular space; and plasma membrane. Is intrinsic component of external side of plasma membrane. Is expressed in foregut-midgut junction. Used to study cone-rod dystrophy 9. Human ortholog(s) of this gene implicated in cone-rod dystrophy 9. Orthologous to human ADAM9 (ADAM metallopeptidase domain 9). [provided by Alliance of Genome Resources, Apr 2022]