Wnt7a - Wnt family member 7A

Enables frizzled binding activity. Involved in several processes, including canonical Wnt signaling pathway; positive regulation of JNK cascade; and response to estradiol. Predicted to be located in cell surface and extracellular matrix. Predicted to be active in Schaffer collateral - CA1 synapse; extracellular space; and glutamatergic synapse. Human ortholog(s) of this gene implicated in Fuhrmann syndrome and Schinzel type phocomelia. Orthologous to human WNT7A (Wnt family member 7A). [provided by Alliance of Genome Resources, Apr 2022]