Mouse
Acvr1 - activin A receptor, type 1
Alias:
ALK2
Acvr
Alk8
SKR1
Alk-2
Tsk7L
ActR-I
ActRIA
Acvr1a
Acvrlk2
D330013D15Rik
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables activin binding activity; transforming growth factor beta binding activity; and transmembrane receptor protein serine/threonine kinase activity. Involved in heart development; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation; and positive regulation of nitrogen compound metabolic process. Acts upstream of or within several processes, including chordate embryonic development; circulatory system development; and gastrulation. Located in apical part of cell. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; limb; male reproductive gland or organ; and sensory organ. Used to study fibrodysplasia ossificans progressiva. Human ortholog(s) of this gene implicated in fibrodysplasia ossificans progressiva. Orthologous to human ACVR1 (activin A receptor type 1). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
6
12
120391 bp
57.23
12
9
Acvr1 Genetics information (-)
GRCm39
Chr : -
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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