Arhgef7 - Rho guanine nucleotide exchange factor 7

Enables protein kinase binding activity. Contributes to small GTPase binding activity. Involved in actin cytoskeleton organization; astrocyte cell migration; and small GTPase mediated signal transduction. Located in cytoplasm; focal adhesion; and growth cone. Part of protein-containing complex. Is active in GABA-ergic synapse. Orthologous to human ARHGEF7 (Rho guanine nucleotide exchange factor 7). [provided by Alliance of Genome Resources, Apr 2022]