Itga6 - integrin subunit alpha 6

Enables laminin binding activity. Involved in cell-cell adhesion; cellular response to organic cyclic compound; and positive regulation of cell-substrate adhesion. Located in adherens junction and filopodium. Part of integrin alpha6-beta4 complex. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and junctional epidermolysis bullosa with pyloric atresia. Orthologous to human ITGA6 (integrin subunit alpha 6). [provided by Alliance of Genome Resources, Apr 2022]