Cited2 - Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Predicted to enable several functions, including LBD domain binding activity; histone acetyltransferase binding activity; and transcription coactivator activity. Involved in several processes, including cell aging; negative regulation of cardiac muscle cell proliferation; and regulation of gene expression. Predicted to be located in chromatin and cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Used to study osteosarcoma. Biomarker of brain ischemia. Human ortholog(s) of this gene implicated in atrial heart septal defect 8 and ventricular septal defect. Orthologous to human CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2). [provided by Alliance of Genome Resources, Apr 2022]