Chrna6 - cholinergic receptor, nicotinic, alpha polypeptide 6

Enables acetylcholine-gated cation-selective channel activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within membrane depolarization and regulation of dopamine secretion. Located in dopaminergic synapse. Part of acetylcholine-gated channel complex. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Is expressed in central nervous system and retina. Orthologous to human CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). [provided by Alliance of Genome Resources, Apr 2022]