Hcn2 - hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

Enables PDZ domain binding activity and molecular adaptor activity. Involved in several processes, including aging; cellular response to aldosterone; and response to cisplatin. Located in several cellular components, including axon; dendrite; and neuronal cell body. Biomarker of dermatitis; meningitis; and visual epilepsy. Human ortholog(s) of this gene implicated in familial febrile seizures 2. Orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2). [provided by Alliance of Genome Resources, Apr 2022]