Rax - retina and anterior neural fold homeobox

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including camera-type eye development; hypothalamus development; and limb development. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in isolated microphthalmia 3. Orthologous to human RAX (retina and anterior neural fold homeobox). [provided by Alliance of Genome Resources, Apr 2022]