Enables isocitrate dehydrogenase (NAD+) activity. Involved in NADH metabolic process; carboxylic acid metabolic process; and tricarboxylic acid cycle. Predicted to be part of mitochondrial isocitrate dehydrogenase complex (NAD+). Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in retinitis pigmentosa 90. Orthologous to human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]